The Lord is at Hand, 6 do not be anxious about anything, but in everything by prayer and supplication with thanksgiving let your requests be made known to God. 7 And the peace of God, which surpasses all understanding, will guard your hearts and your minds in Christ Jesus.
How does one find perfect peace? In a world filled with violence, rejection, suffering, and turmoil, how can anyone find peace? First, peace is revealed in a trust in Jesus Christ as Lord and Savior. This is a general peace that accompanies belief. When a believer confesses faith, they are granted a sense of eternal peace through the assurance that they will be welcomed into eternal dwellings. However, the peace that Paul is proposing in verse 7 is a peace that is transcendent even of current circumstances. A prisoner who could not be overtaken or defeated by any circumstance, Paul gives the reader insight into how a person can achieve perfect peace amidst a life filled with suffering and strife.
Consider the exhortation of verse 6, “…in everything by prayer and supplication with thanksgiving let your request be made known to God” (ESV). At the root of Paul’s admonition is thanksgiving. The basis of approaching the Holy God of the Universe is to do so with a spirit of gratitude. The word translated as thanksgiving is the same word used to refer to communion in the early church fathers. This word denotes a sort of connection with God that exalts Him as Lord and submits to His design and will. Thanksgiving necessitates surrender. So it is here, in order to find peace, one must be willing to surrender their own control. Prayers and requests must be founded on a motivation of gratitude no matter what the outcome of the prayers may be.
In addition to a spirit of gratitude, the target of effective prayer and supplication is God. He is the one to whom Christians direct their requests in times of anxiety. It is a peculiar reality that Christians often do not pursue prayer as their first course of action. When anxious feelings strike the soul, the often Western Christians will set their minds to solving the problem. They will seek to gather information, speak to others, seek out counsel, identify the solution, and even attempt to escape their own predisposed condition. Paul’s instructions are vastly different. Christians are not supposed to be anxious, but are supposed to combat anxiety with prayer first and foremost. Believers are designed to lean on God for comfort, yet almost every Christian conference in the west deals with being a better leader or developing a better strategy. There is almost never an emphasis on simply obeying this simple exhortation: pray. Is it any wonder that the western church is fraught with anxiety? As a culture, western Christianity has attempted to address moments of trouble and suffering with their intellect, financial means, and talents. Paul says peace will come if we pray with thanksgiving.
Take note of the kind of peace that comes. It is not merely circumstantial or temporary. The type of peace that Paul is proclaiming is one that is transcendent. It surpasses understanding. This is the sort of peace that baffles the world. This is the sort of peace that challenges human concepts of comfort. This is the sort of peace that can lose everything and rejoice in the face of certain death. This is the peace only Christ can give. This peace is so powerful and profound that it will guard those who have it.
Paul cites that this peace will specifically guard the “heart” and “mind.” Take encouragement dear Christian. God is concerned about your heart. He has not left you to struggle. He walks through your pain and suffering with you to guard your heart. Trust Him. Nor has God abandoned you to your own reason. He guides you and leads you on in your search for understanding amidst pain. You have not been left alone. God has come and is here with you, offering you peace in surrender to Him.
 Balz, H. R., & Schneider, G. (1990–). Exegetical dictionary of the New Testament (Vol. 2, p. 88). Grand Rapids, Mich.: Eerdmans.
 For a more full explaination of the word for thanksgiving and the concept of eucharist, I highly recommend Ann Voskamp’s 1,000 Gifts.